Principal Investigators

  • Gregory J. Czarnota, PhD, MD

    Ph.D., MD, FRCPC, Scientist

    Dr. Czarnota is conducting research focused on using ultrasound imaging and spectroscopy at conventional and high frequencies to detect apoptosis and other forms of cell death in response to chemotherapy and radiation therapy. He is also interested in the role of blood vessels in tumour radiation response and has also pioneered novel biophysical vascular destruction strategies that target tumour blood vessels.

  • Michael C. Kolios, PhD

    Professor, Department of Physics

    Dr. Kolios is a physicist who's research primarily focuses on the source of scattering in ultrasound backscatter. His laboratory is multidisciplinary and uses state of the art ultrasound technology (conventional, high and ultra-high frequencies; acoustic microscopy), Optoacoustic Imaging / Optoacoustic microscopy. He is also interested in developing a better understanding of the use of microbubbles for Imaging and Therapy and the use of Optical Coherence Tomography in treatment monitoring.

  • Gregory Stanisz, PhD

    Ph.D., Senior Scientist

    Dr. Stanisz’s studies aim to develop magnetic resonance imaging (MRI) methods to improve specificity and sensitivity of noninvasive image methods in characterizing tissue pathology. His research team uses MRI in animal models of disease and in patients.

  • Stanley Liu, PhD

    Ph.D., MD, FRCPC, Scientist

    Dr. Liu's research aims to improve treatment outcomes for cancer patients by researching and integrating novel, molecular, targeted agents with radiotherapy. More than 50% of cancer patients will receive radiotherapy sometime during their cancer treatment; thus, it is important to research ways to improve the efficacy of this treatment.

  • Arjun Sahgal, MD


    Dr. Sahgal's research focus relates to his training and clinical expertise in spinal metastases, brain metastases and primary central nervous system tumours. His primary research area is in technical evaluation and clinical trials specific to stereotactic body radiotherapy of spinal tumours and brain metastases. In line with high-precision radiotherapy treatments, Dr. Sahgal participates in the development of focal non-radiotherapeutic modalities for spine and brain tumours using photodynamic therapy and magnetic resonance imaging-guided ultrasound technology.

  • Ali Sadeghi-Naini, PhD


    The focus of Dr. Sadeghi-Naini's research is on developing computer-aided image-guided technologies to improve personalized cancer therapeutics. In particular, he is interested in developing integrated imaging and computational frameworks to detect and characterize cancer, to facilitate cancer-targeting interventions and to evaluate response to treatment.

  • Angus Lau, PhD

    Our aim is to develop and enhance the use of ultrasound techniques to improve cancer treatment. Our primary focus is the development of quantitative ultrasound (QUS) methods to monitor cancer therapy response. In addition, we have are developing novel ultrasound-based therapies to improve current conventional cancer treatments. Our ultimate goal is to implement both clinically at the end of the proposed research period, with clinical evaluations of enhanced imaging and cancer treatment derived from these research objectives.