Principal Investigators

Michael C. Kolios, PhD

Professor, Department of Physics
Associate Dean of Science,
Research and Graduate Studies
Faculty of Science Office:
Rm VIC-733:
285 Victoria Street,
Toronto, ON
M5B 2K3

Education:

PhD., Medical Physics, Department of Medical Biophysics, U of Toronto 1998
M.Sc., Medical Physics, Department of Medical Biophysics, U of Toronto 1994
B.Sc. Physics, (Minor: Computer Science), Department of Physics, U of Waterloo 1991

Appointments and Affiliations:

Associate Professor, Department of Physics (prior Mathematics, Physics and Computer Science), Ryerson University
Adjunct Professor, Department of Medical Biophysics, Full Member School Graduate Studies, University of Toronto
Adjunct Professor, Department of Electrical and Computer Engineering, Ryerson University
Canada Research Chair, TierII, Biomedical Applications of Ultrasound
Graduate Program in Physics, in the field of Biomedical Physics, Ryerson University

Research Focus:

Specialization:

Ultrasound imaging and therapeutics, Ultrasound imaging, Optical Coherence Tomography, Photoacoustics, Theranostic agent development, Heat transfer in tissue, Thermal Therapies

Research Projects:

My research interests are in the application of ultrasound in medicine and the modeling of heat transfer in tissues. I am currently examining the potential of using high frequency ultrasound imaging (20-60MHz) for the detection of cell death. Even though at these frequencies we cannot resolve individual cells, we can examine the ultrasound backscatter from cell ensembles to make inferences about the state of the cells. We have found that the ultrasound backscatter from cells dying either by apoptosis (a form of cell suicide) or necrosis increases, and the frequency dependence of the backscatter power spectra can potentially be used to differentiate between the two, at least in the in vitro systems we have used to date. I am collaborating with researchers at the Sunybrook Hospital in Toronto to determine whether this methodology can also be used in animal tumor models (to detect the death of cancer cells), and we are currently participating in a clinical trial involving cancer patients with superficial tumors. We have developed theoretical models to better understand the backscattering process, and have used experimental systems to examine the backscatter from objects on the scale of cells for which we know their properties. Ultrasonic characterization of cells and cellular components is thus an ongoing interest in the lab. Ultrasound at higher intensities can be used to destroy tissues rather than image them. We have developed theoretical models to estimate temperatures during the heating of tissue using ultrasound or other sources (such as laser), and are currently examining the effect of blood flow on these heating patterns. Furthermore I am investigating the use of an acoustic camera to monitor the treated tissue non-invasively. The acoustic camera records how ultrasound is attenuated rather than detecting the backscatter as conventional ultrasound does. Finally, I have incorporated in my research program optical techniques as a source of new contrast: optical coherence tomography and photoacoustic imaging, which currently form a substantial core of my research program.

Publications:

2017

1. Spatial interference encoding patterns based photoacoustic microscopy

Amihai Meiri, Eric M. Strohm, Michael C. Kolios, Zeev Zalevsky (2017)  Optics Communications, Volume 401, 15 October 2017, Pages 23-28
https://doi.org/10.1016/j.optcom.2017.05.002
 

2. Low-power noncontact photoacoustic microscope for bioimaging applicationsKrishnan Sathiyamoorthy, Eric M. Strohm and Michael C. Kolios (2017)
J. Biomed. Opt. 22(4), 046001 (Apr 04, 2017). http://doi.org/10.1117/1.JBO.22.4.046001
 

3. Stable microfluidic flow focusing using hydrostatics
Vaskar Gnyawali, Mohammadali Saremi, Michael C. Kolios, and   Scott S. H. Tsai (2017)
Biomicrofluidics 11, 034104 (2017); doi: http://dx.doi.org/10.1063/1.4983147
 

4. Honey, I shrunk the bubbles: microfluidic vacuum shrinkage of lipid-stabilized microbubblesVaskar Gnyawali, Byeong-Ui Moon, Jennifer Kieda, Raffi Karshafian, Michael C. Kolios and  Scott S. H. Tsai (2017)
Soft Matter, 2017, http://dx.doi.org/10.1039/c7sm00128b
https://rsc.altmetric.com/details/18532311
 

5. Photoacoustic signal characterization of cancer treatment response: Correlation with changes in tumor oxygenationEno Hysi, Lauren A. Wirtzfeld, Jonathan P. May, Elijus Undzys, Shyh-Dar Li, Michael C. Kolios (2017)
Photoacoustics Volume 5, March 2017, Pages 25–35 http://doi.org/10.1016/j.pacs.2017.03.003
 

6. Effect of chromatin structure on quantitative ultrasound parameters
Maurice Pasternak, Lilian Doss, Golnaz Farhat, Azza Al-Mahrouki, Christina Hyunjung Kim, Michael Kolios, William Tyler Tran, Gregory J. Czarnota (2017)
Oncotarget. ; 8:19631-19644. http://doi.org/10.18632/oncotarget.14816
 

7. Photoacoustic field calculation for nonspherical axisymmetric fluid particles
Ratan K Saha, Subhajit Karmakar, Arunabha Adhikari and Michael C Kolios (2017)
Biomedical Physics & Engineering Express, Volume 3, Number 1 015017 https://doi.org/10.1088/2057-1976/aa555f
 
2016
 

1. Photoacoustic Imaging of Cancer Treatment Response: Early Detection of Therapeutic Effect from Thermosensitive Liposomes
May JP, Hysi E, Wirtzfeld LA, Undzys E, Li S-D, Kolios MC(2016)
PLoS ONE 11(10): e0165345. http://dx.doi.org/10.1371/journal.pone.0165345
 

2. Assessment of the Nucleus-to-Cytoplasmic Ratio in MCF-7 Cells Using Ultra-high Frequency Ultrasound and Photoacoustics
M.J. Moore, E. M. Strohm and M. C. Kolios (2016)
Int J Thermophys  (2016) 37:118 http:dx.doi.org/10.1007/s10765-016-2129-y
 

3. Magnetic nanoparticle-promoted droplet vaporization for in vivo stimuli-responsive cancer theranostics
Yang Zhou, Ronghui Wang, Zhaogang Teng, Zhigang Wang, Bing Hu, Michael Kolios, Hangrong Chen, Nan Zhang, Yanjie Wang, Pan Li, Xing Wu, Guangming Lu, Yu Chen and Yuanyi Zheng (2016)
NPG Asia Materials (2016) 8, e313; http://dx.doi.org/10.1038/am.2016.146
 

4. Biodegradable polymeric nanoparticles containing gold nanoparticles and Paclitaxel for cancer imaging and drug delivery using photoacoustic methods
Yanjie Wang, Eric M. Strohm, Yang Sun, Zhaoxia Wang, Yuanyi Zheng, Zhigang Wang, and Michael C. Kolios (2016)
Biomedical Optics Express Vol. 7, Issue 10, pp. 4125-4138 (2016) http://dx.doi.org/10.1364/BOE.7.004125
 

5. High-frequency ultrasound detection of cell death: Spectral differentiation of different forms of cell death in vitro
Maurice M. Pasternak, Ali  Sadeghi-Naini, Shawn M. Ranieri, Anoja  Giles, Michael L. Oelze, Michael C. Kolios and Gregory J. Czarnota (2016)
Oncoscience  http://dx.doi.org/10.18632/oncoscience.319
 

6. Synthesis Of Stable Multifunctional Perfluorocarbon Nanoemulsions For Cancer Therapy And ImagingDonald Anthony Fernandes, Dennis Denzil Fernandes, Yuchong Li, Yan Wang, Zhenfu Zhang, Dérick Rousseau, Claudiu C Gradinaru, and Michael C. Kolios (2016)Langmuir, Just Accepted Manuscript http://dx.doi.org/10.1021/acs.langmuir.6b01867
 

7. Pseudo-Inverse (PI) Decoding process in Delay encoded Synthetic Transmit Aperture (DE-STA) Imaging
Ping Gong, Michael C. Kolios, Yuan Xu (2016)
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control  vol. 63, no. 9, pp. 1372-1379, Sept. 2016. http://dx.doi.org/10.1109/TUFFC.2016.2578952
 

8. Simultaneous assessment of red blood cell aggregation and oxygen saturation under pulsatile flow using high-frequency photoacoustics
Tae-Hoon Bok, Eno Hysi, and Michael C. Kolios (2016)
Biomedical Optics Express July 2016 Volume 7(7) #262587 http://dx.doi.org/10.1364/BOE.7.002769
 

9. Single cell photoacoustic microscopy: a review
Eric M. Strohm, Michael J. Moore, Michael C. Kolios (2016)
IEEE Journal of Selected Topics in Quantum Electronics Volume 22, Issue 3, May-June 2016 http://dx.doi.org/10.1109/JSTQE.2015.2497323
 

10. Temperature dependence of acoustic harmonics generated by nonlinear ultrasound wave propagation in water at various frequencies
Borna Maraghechi, Mojtaba H. Hasani, Michael C. Kolios, and Jahan Tavakkoli (2016)
Journal of the Acoustical Society of America 139, 2475  http://dx.doi.org/10.1121/1.4946898
 

11. High resolution ultrasound and photoacoustic imaging of single cells
Eric M. Strohm, Michael J. Moore, Michael C. Kolios (2016)
Photoacoustics Volume 4, Issue 1, March 01, 2016, Pages 36-42 http://dx.doi.org/10.1016/j.pacs.2016.01.001
 

12. High-frequency ultrasound analysis of post-mitotic arrest cell death
Maurice M. Pasternak, Lauren A. Wirtzfeld, Michael C. Kolios and Gregory J. Czarnota (2016)
Oncoscience  http://dx.doi.org/10.18632/oncoscience.301

 
2015
 

1. Quantification of Ultrasonic Scattering Properties of In Vivo Tumor Cell Death in Mouse Models of Breast Cancer
Hadi Tadayyon, Lakshmanan Sannachi, Ali Sadeghi-Naini, Azza Al-Mahrouki, William T. Tran, Michael C. Kolios, Gregory J. Czarnota (2015)
Translational Oncology 8(6) pp. 463–473 http://dx.doi.org/10.1016/j.tranon.2015.11.001
 

2. Optical coherence tomography spectral analysis for detecting apoptosis in vitro and in vivo
Golnaz Farhat, Anoja Giles, Michael C. Kolios, Gregory J. Czarnota (2015)
Journal of Biomedical Optics 20(12), 126001 http://dx.doi.org/10.1117/1.JBO.20.12.126001
 

3. Delay-Encoded Transmission and Image Reconstruction Method in Synthetic  Transmit Aperture Imaging
Ping Gong, Michael C. Kolios, and Yuan Xu (2015)
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Oct. 62(10):  1745 – 1756  http://dx.doi.org/10.1109/TUFFC.2015.007005
 

4. Properties of Cells through Life and Death – An Acoustic Microscopy Investigation
Pasternak MM, Strohm EM, Berndl ES, Kolios MC. (2015)
Cell Cycle.  Jul 15:0. [Epub ahead of print] http://dx.doi.org/10.1080/15384101.2015.1069925
 

5. High-Frequency Acoustic Impedance Imaging of Cancer Cells.
Fadhel MN, Berndl ES, Strohm EM, Kolios MC. (2015)
Ultrasound in Medicine and  Biology Jul 9. pii: S0301-5629(15)00400-7. http://dx.doi.org/10.1016/j.ultrasmedbio.2015.06.003
 

6. Temperature dependence of acoustic harmonics generated by nonlinear ultrasound beam propagation in ex vivo tissue and tissue-mimicking phantoms.
Maraghechi B, Kolios MC, Tavakkoli J. (2015)
International Journal of Hyperthermia Jul 1:1-8. [Epub ahead of print] http://dx.doi.org/10.3109/02656736.2015.1052856
 

7. Classification of blood cells and tumor cells using label-free ultrasound and photoacoustics.
Strohm EM, Kolios MC. (2015)
Cytometry A. Jun 16. http://dx.doi.org/10.1002/cyto.a.22698. [Epub ahead of print]
 

8. Exact solution for a photoacoustic wave from a finite-length cylindrical source
Jason Zalev and Michael C. Kolios (2015)
Journal of the Acoustical Society of  America 137 (4), Pages: 1675–1682 DOI: http://dx.doi.org/10.1121/1.4916273
 

9. Quantitative Ultrasound Spectroscopic Imaging for Characterization of Disease Extent in Prostate Cancer Patients
Ali Sadeghi-Naini, Ervis Sofroni, Naum Papanicolau, Omar Falou, Linda Sugar, Gerard Morton, Martin J. Yaffe, Robert Nam, Alireza Sadeghian, Michael C. Kolios, Hans T. Chung, Gregory J. Czarnota (2015)
Translational Oncology Volume 8, Issue 1, Pages 25–34 DOI: http://dx.doi.org/10.1016/j.tranon.2014.11.005
 

10. Influence of the pressure-dependent resonance frequency on the bifurcation structure and backscattered pressure of ultrasound contrast agents: a numerical investigation
Amin Jafari Sojahrood, Omar Falou, Robert Earl, Raffi Karshafian, Michael C. Kolios (2015)
Nonlinear Dynamics  1-16   –  DOI: 10.1007/s11071-015-1914-7

 
2014
 

1. Laser-Activatible PLGA Microparticles for Image-Guided Cancer Therapy In Vivo
Yang Sun, Yanjie Wang, Chengcheng Niu, Eric M. Strohm, Yuanyi Zheng, Haitao Ran, Rongzhong Huang, Di Zhou, Yuping Gong, Zhigang Wang, Dong Wang and Michael C. Kolios (2014)
Advanced Functional Materials  –  DOI: 10.1002/adfm.201402631
(commentary: Cancer treatment based on PLGA microparticles, – Materials Views – posted October 2014)
 

2. Modeling photoacoustic spectral features of micron-sized particles
Eric M Strohm, Ivan Gorelikov, Naomi Matsuura and Michael C Kolios (2014)
Physics in Medicine & Biology 59  5795–5810
 

3. Speckle statistics in OCT images: Monte Carlo simulations and experimental studies
Mikhail Yu. Kirillin, Golnaz Farhat, Ekaterina A. Sergeeva, Michael C. Kolios, and Alex Vitkin (2014)
Optics Letters 39(2)  3472-3475
 

4. Optoacoustic characterization of prostate cancer in an in vivo transgenic murine model
Michelle P. Patterson, Christopher B. Riley, Michael C. Kolios, William M. Whelan (2014)
J. Biomed. Opt. 19(5), 056008 (May 09, 2014). doi:10.1117/1.JBO.19.5.056008
 

5. Early prediction of therapy responses and outcomes in breast cancer patients using textural characteristics of quantitative ultrasound spectral parametric maps
Ali Sadeghi-Naini, Lakshmanan Sannachi, Kathleen Pritchard, Maureen Trudeau, Sonal Gandhi, Frances C. Wright, Judit Zubovits, Martin J. Yaffe, Michael C. Kolios, Gregory J. Czarnota (2014)
Oncotarget (5)
 

6. Photoacoustic detection and optical spectroscopy of HIFU lesions
Mosa Alhamami, Michael C. Kolios, and Jahan Tavakkoli (2014)
Medical Physics 41, 053502 (2014); doi: 10.1118/1.4871621
 

7. Optical coherence tomography detection of shear wave propagation in inhomogeneous tissue equivalent phantoms and ex-vivo carotid artery samples
Marjan Razani, Timothy W.H. Luk, Adrian Mariampillai, Peter Siegler, Tim-Rasmus Kiehl, Michael C. Kolios, and Victor X.D. Yang (2014)
Biomedical Optics Express,  March 2014, Vol. 5 No.3,   doi:10.1364/BOE.5.000895
 

8. Personalization of breast cancer chemotherapy using noninvasive imaging methods to detect tumor cell death responses
Lakshmanan Sannachi, Hadi Tadayyon, Ali Sadeghi-Naini, Michael C. Kolios, Gregory Czarnota (2014)
Breast Cancer Management, January 2014, Vol. 3, No. 1, Pages 31-35

 
2013
 

1. High frequency label-free photoacoustic microscopy of single cells
Eric M. Strohm, Elizabeth S. L. Berndl, and Michael C. Kolios (2013)
Photoacoustics Volume 1, Issues 3-4
 

2. Probing Red Blood Cell Morphology Using High-Frequency Photoacoustics
Eric M. Strohm, Elizabeth S. L. Berndl, and Michael C. Kolios (2013)
Biophysical Journal Volume 105 1–9
https://cell.altmetric.com/details/1600902
(see also press coverage: http://www.physics.ryerson.ca/node/1769)
 

3. Low-frequency quantitative ultrasound imaging of cell death in vivo
Ali Sadeghi-Naini, Naum Papanicolau, Omar Falou, Hadi Tadayyon, Justin Lee, Judit Zubovits, Raffi Karshafian, Azza Al-Mahrouki, Anoja Giles, Michael C. Kolios and Gregory J. Czarnota (2013)
Medical Physics 40 (8)
 

4. Non-invasive Monitoring of Ultrasound-Stimulated Microbubble Radiation Enhancement Using Photoacoustic Imaging
Kaleigh Briggs, Azza Al Mahrouki, Joris Nofiele, Ahmad El-Falou, Martin Stanisz. Hyunjung Christina Kim, Michael C. Kolios, Gregory J. Czarnota (2013)
TCRT Express 1(2) 143-152 (e600266)
 

5. Conventional frequency ultrasonic biomarkers of cancer treatment response in vivo
Ali Sadeghi-Naini, Omar Falou, Hadi Tadayyon, Azza Al-Mahrouki, William Tran, Naum Papanicolau, Michael C Kolios, Gregory J Czarnota (2013)
Translational Oncology 6 (3) 234-243
 

6. Quantitative Ultrasound Evaluation of Tumour Cell Death Response in Locally Advanced Breast Cancer Patients Receiving Chemotherapy
Ali Sadeghi-Naini, Naum Papanicolau, Omar Falou, Judit Zubovits, Rebecca Dent, Sunil Verma, Maureen E. Trudeau, Jean Francois Boileau, Jacqueline Spayne, Sara Iradji, Ervis Sofroni, Justin Lee, Sharon Lemon-Wong, Martin J Yaffe, Michael C. Kolios, and Gregory J. Czarnota (2013)
Clinical Cancer Research 19 (8) 2163-2174
 

7. Investigating longitudinal changes in the mechanical properties of MCF-7 cells exposed to paclitaxol using particle tracking microrheology
Ahmed El Kaffas, Devesh Bekah, Min Rui, J Carl Kumaradas and Michael C Kolios (2013)
Physics in Medicine and Biology 58 (2013) 923–936
(commentary: Cell elasticity indicates therapy responseMedical Physics Web – posted Feb 2013)

 
2012
 

1. Photoacoustic ultrasound spectroscopy for assessing red blood cell aggregation and oxygenation
Eno Hysi, Ratan K. Saha and Michael C. Kolios (2012)
Journal of Biomedical Optics 17(12), 125006
 

2. Acoustic and photoacoustic characterization of micron-sized perfluorocarbon emulsions
Eric M. Strohm, Ivan Gorelikov, Naomi Matsuura, Michael C. Kolios (2012)
Journal of Biomedical Optics 17(9), 096016
 

3. Surface modes and acoustic scattering of microspheres and ultrasound contrast agents
Omar Falou, Amin Jafari Sojahrood, J. Carl Kumaradas, and Michael C. Kolios (2012)
The Journal of the Acoustical Society of America 133 (5)  – 1820-1829
 

4. On the use of photoacoustics to detect red blood cell aggregation
Eno Hysi, Ratan K. Saha and Michael C. Kolios (2012)
Biomedical Optics Express, Vol. 3, No. 9, Pages 2326-2338
 

5. Imaging innovations for cancer therapy response monitoring
Ali Sadeghi-Naini, Omar Falou, John M Hudson, Colleen Bailey, Peter N Burns, Martin J Yaffe, Greg J Stanisz, Michael C Kolios & Gregory J Czarnota (2012)
Imaging in Medicine, Voume 4 Number 3 , Pages  311-327
 

6. Quantitative Ultrasound for the Monitoring of Novel Microbubble and Ultrasound Radiosensitization
Lee J, Karshafian R, Papanicolau N, Giles A, Kolios MC, Czarnota GJ. (2012)
Ultrasound in Medicine and Biology Volume 38, Issue 7, Pages 1212–1221
Classification of the nonlinear dynamics and bifurcation structure of ultrasound contrast agents excited at higher multiples of their resonance frequency
Amin Jafari Sojahrood and Michael C. Kolios (2012)
Physics Letters A, Volume 376, Issue 33 pp. 2222–2229
 

7. Validity of a theoretical model to examine blood oxygenation dependent optoacoustics
Ratan K. Saha
, Subhajit Karmakar, Eno Hysi, Madhusudan Roy, and Michael C. Kolios (2012)
Journal of Biomedical Optics 17(5), 055002
 

8. Feasibility of optical coherence elastography measurements of shear wave propagation in homogeneous tissue equivalent phantoms
Marjan Razani, Adrian Mariampillai, Cuiru Sun, Timothy W. H. Luk, Victor X. D. Yang, and Michael C. Kolios (2012)
Biomedical Optics Express, Vol. 3, Issue 5, pp. 972-980

 
2011
 

1. Effects of erythrocyte oxygenation on optoacoustic signals
Ratan K. Saha
and Michael C. Kolios (2011
Journal of Biomedical Optics 16, 115003; doi:10.1117/1.3655355
 

2. Detecting apoptosis using dynamic light scattering with optical coherence tomography
Golnaz Farhat, Adrian Mariampillai, Victor X. D. Yang, Gregory J. Czarnota and Michael C. Kolios (2011),
Journal of Biomedical Optics 16, 070505 (Jul 18, 2011); doi:10.1117/1.3600770
 

3. Effects of Cell Spatial Organization and Size Distribution on Ultrasound Backscattering
Ratan K. Saha and Michael C. Kolios (2011)
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
, vol.58(10)  2118-2131
<   4. A simulation study on photoacoustic signals from red blood cells
Ratan K. Saha and Michael C. Kolios (2011)
The Journal of the Acoustical Society of America 129 (5)  – 2935–2943
[URL: http://link.aip.org/link/?JAS/129/2935 – DOI: 10.1121/1.3570946]
 

5. Vaporization of perfluorocarbon droplets using optical irradiation
Eric Strohm, Min Rui, Ivan Gorelikov, Naomi Matsuura, and Michael Kolios (2011)
Biomedical Optics Express, Vol. 2, Issue 6, pp. 1432-1442
 

6. Detecting cell death with optical coherence tomography and envelope statistics
Golnaz Farhat, Victor X. D. Yang, Gregory J. Czarnota and Michael C. Kolios (2011)
Journal of Biomedical Optics 16(2) – 026017
 

7. Hybrid Quantum Dot−Fatty Ester Stealth Nanoparticles: Toward Clinically Relevant in Vivo Optical Imaging of Deep Tissue
Adam J. Shuhendler, Preethy Prasad, Ho-Ka Carol Cha†, Claudia R. Gordijo, Behrouz Soroushian, Michael Kolios, Kui Yu, Peter J. O’Brien, Andrew Michael Rauth, and Xiao Yu Wu (2011)
ACS Nano 5(3) – 1958-1966

 
2010
 
1. Study of laser-induced thermoelastic deformation of native and coagulated ex-vivo bovine liver tissues for estimating their optical and thermomechanical properties
Behrouz Soroushian, William M. Whelan, Michael C. Kolios (2010)
Journal of Biomedical Optics 15(6) – 065002
 
2. Quantitative Measurements of Apoptotic Cell Properties Using Acoustic Microscopy
Eric M. Strohm, Gregory J. Czarnota, and Michael C. Kolios (2010)
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 57, no. 10
 
3. An increase in cellular size variance contributes to the increase in ultrasound backscatter during cell death 
Roxana M. Vlad
, Ratan K Saha, Nehad M. Alajez, Shawn Ranieri, Gregory J. Czarnota and Michael C. Kolios (2010)
Ultrasound in Medicine and Biology 36 (9) 1546-1558
 
4. The measurement of ultrasound scattering from individual micron-sized objects and its application in single cell scattering
Omar FalouMin Rui, Ahmed El Kaffas,  J. Carl Kumaradas and Michael C. Kolios (2010)
The Journal of the Acoustical Society of America 128 (2) 894–902
[selected for the August 15, 2010 issue of Virtual Journal of Biological Physics Research]
 
5. Evaluating the extent of cell death in 3D high frequency ultrasound by registration with whole-mount tumor histopathology
Roxana M. Vlad, Michael C. Kolios, Joanne L. Moseley, Gregory J. Czarnota, Kristy K. Brock (2010)
Medical Physics 37 (8) 4288-4297
[selected for the August 1, 2010 issue of Virtual Journal of Biological Physics Research]
 
6. Single cell size estimation from backscattered spectrum by using some weak acoustic scattering approximations
Ratan K Saha, Subodh K Sharma and Michael C Kolios (2010)
Canadian Acoustics / Acoustique canadienne 38 (2) 31-34
 
7. Ultrasound detection of cell death
Gregory J. Czarnota and Michael C. Kolios (2010)
Imaging in Medicine 2(1) 17-28
 
2009
 
1. Potential use of ultrasound for the detection of cell changes in cancer treatment
Michael C. Kolios and Gregory J. Czarnota (2009)
Future Oncology 5(10) 1527-1532
 
2. Quantitative Ultrasound Characterization of Responses to Radiotherapy in Cancer Mouse Models
Vlad RM, Brand S, Giles A, Kolios MC, Czarnota GJ. (2009)
Clincal Cancer Research 15(6):2067-75
 
3. Monitoring of cell death in epithelial cells using high frequency ultrasound spectroscopy
Brand S, Solanki B, Foster DB, Czarnota GJ, Kolios MC. (2009)
Ultrasound in Medicine and Biology 35(3):482-93

 
2008
 
1. Quantitative Ultrasound Characterization of Cancer Radiotherapy Effects In Vitro
Roxana M. Vlad, Nehad M. Alajez, Anoja Giles, Michael C. Kolios, Gregory J. Czarnota (2008)
International Journal of Radiation Oncology Biology Physics, 72 (4): 1236-1243
 
2. A study of high frequency ultrasound scattering from non-nucleated biological specimens
Omar Falou, Ralph E. Baddour, George Nathanael, Gregory J. Czarnota, J. Carl Kumaradas and Michael C. Kolios (2008)
The Journal of the Acoustical Society of America 124(5): EL278-EL283
[selected  for inclusion in the Virtual Journal of Biological Physics Research / Volume 16 / Issue 8 / 2008]
 
3. Detecting the Effects of Photodynamic Therapy in vivo by High Frequency Ultrasound Spectroscopy: a Novel Way of Monitoring Tumour Response
Behzad Banihashemi, Roxana Vlad, Bane Debeljevic, Anoja Giles, Michael C. Kolios, Gregory J. Czarnota (2008)
Cancer Research 68(20): 8590-8596
 
4. High frequency ultrasound tissue characterization and acoustic microscopy of intracellular changes
Sebastian Brand, Weiss EC, Lemor RM, and Kolios M.C. (2008)
Ultrasound in Medicine and Biology 34(9): 1396-1407
 
2007
 
1. Parametric analysis of ultrasound backscatter signals for monitoring cancer cell structural changes during cancer treatment
Harshitha Nallapareddy, Sridhar Krishnan and Michael Kolios (2007)
Canadian Acoustics 35(2): 47-54
 
2. High-Frequency Ultrasound Assessment of Antimicrobial Photodynamic Therapy In Vitro
Ralph E. Baddour, Farhan N. Dadani, Michael C. Kolios and Stuart K. Bisland (2007)
Journal of Biological Physics 33:61–66
 
3. Ultrasonic Characterization of Whole Cells and Isolated Nuclei,
Linda Taggart, Ralph E. Baddour, Anoja Giles, Gregory J. Czarnota and Michael C. Kolios (2007)
Ultrasound in Medicine and Biology 33 (3): 389-401
 
4. Wide dynamic range detection of bidirectional flow in Doppler optical coherence tomography using a two-dimensional Kasai estimator
Darren Morofke, Michael C. Kolios, I. Alex Vitkin and Victor X. D. Yang (2007)
Optics Letters 32 (3): 253-255
[Selected for inclusion in the Virtual Journal of Biological Physics Research – Jan 15 2007 issue]
 
5. The fluid and elastic nature of nucleated cells: Implications from the cellular backscatter response
Ralph E. Baddour and Michael C. Kolios (2007)
JASA Express Letters 121 (1): 16-22

 
2006
 
1. An Investigation of the Use of Transmission Ultrasound to Measure Acoustic Attenuation Changes in Thermal Therapy
Parmar N. and Kolios M.C. (2006)
Medical and Biological Engineering and Computing 44:583-591

 
2005
 
1. Monitoring Structural Changes in Cells with High Frequency Ultrasound Signal Statistics
A.S. Tunis G.J. Czarnota, A. Giles, M.D. Sherar, J.W. Hunt and M.C. Kolios (2005)
Ultrasound in Medicine and Biology
31(8), 1041-1049
 
2. High-frequency ultrasound scattering from microspheres and single cells
R. E. Baddour, M. D. Sherar, J. W. Hunt, G. J. Czarnota, M. C. Kolios (2005)
Journal of  the Acoustical Society of  America, 117(2), 934-943
[Selected for inclusion in the Virtual Journal of Biological Physics Research – Feb 1 2005 issue]
 
3. High-frequency ultrasound for monitoring changes in liver tissue during preservation
Roxana M. Vlad; Gregory J. Czarnota; Anoja Giles; Michael D. Sherar; John W. Hunt; Michael C. Kolios (2005)
Physics in Medicine and Biology
, 50(2) 197-213

 
2003
 

1. Changes in dielectric properties at 460 kHz of kidney and fat during heating: importance for radio-frequency thermal therapy
Mihaela Pop, Andrea Molckovsky, Lee Chin, Michael C Kolios, Michael A S Jewett and Michael D Sherar (2003)
Physics in Medicine and Biology 48, 2509-2525

 
2002
 

1. Ultrasonic spectral parameter imaging of apoptosis
Kolios M.C., Czarnota G.J., Lee M. , Hunt J.W. and Sherar M.D. (2002)
Ultrasound in Medicine and Biology 28(5), 589-597
 

2. A model based upon pseudo-regular spacing of cells combined with the randomization of nuclei can explain the significant changes in high-frequency ultrasound during apoptosis
Hunt J.W., Worthington A., Xuan A., Kolios M.C., Czarnota G.J. and Sherar M.D. (2002)
Ultrasound in Medicine and Biology 28(2), 217-226

 
2000
 

1. Comparison of thermal damage calculated using magnetic resonance thermometry with magnetic resonance imaging post treatment and histology after interstitial microwave thermal therapy of rabbit brain
M. D Sherar, J. A. Moriarty, M.C. Kolios, J.C. Chen, R.D. Peters, L.C. Ang, R.S. Hinks, R.M. Henkelman, M.J. Bronskill, W. Kucharczyk (2000)
Physics in Medicine and Biology 45, 3563-3576
 

2. The Effects of Dynamic Optical Properties During Interstitial Laser Photocoagulation
Iizuka M.N., Vitkin A.I., Kolios M.C., Sherar M.D. (2000)
Physics in Medicine and Biology 45, 1335-1357

 
1999
 

1. Ultrasonic imaging of apoptosis: high-resolution non-invasive imaging of programmed cell death in vitro, in situ and in vivo
Czarnota G.J., Kolios M.C., Abraham J., Portnoy M., Ottensmeyer F.P., Hunt, J.W. and Sherar M.D.(1999)
British Journal of Cancer 81(3), 520-527
 

2. An investigation of the flow dependence of temperature gradients near large vessel during steady state and transient tissue heating
Kolios M.C., Worthington A.E., Holdsworth D.W., Sherar M.D. and Hunt J.W. (1999)
Physics in Medicine and Biology 44(6), 1479-1497

 
1998
 

1. A Theoretical Comparison of Energy Sources: Microwave, Ultrasound and Laser, for Interstitial Thermal Therapy
Skinner M., Iizuka M., Kolios M.C. and Sherar M.D. (1998)
Physics in Medicine and Biology 43(12), 3535-3547
 

2. Experimental evaluation of two simple thermal models using transient temperature analysis
Kolios M.C., Worthington A. E., Sherar M.D. and Hunt J.W. (1998)
Physics in Medicine and Biology 43(11), 3325-3340

 
1997
 

1. Ultrasonic imaging of viable, dead and apoptotic cells
Czarnota G.J.* , Kolios M.C.* , Vaziri H.* , Benchimol S., Ottensmeyer F.P., Sherar M.D. and Hunt J.W. (1997)
Ultrasound in Medicine and Biology 23(6), 961-965 * authors have made equal contribution
 

2. Magnetic resonance imaging of temperature changes during interstitial microwave heating: a phantom study
Vitkin I.A., Moriarty J.A., Peters R.D., Kolios M.C., Gladman A.S., Chen J.C., Hinks R.S., Hunt J.W., Wilson B.C., Easty A.T., Bronskill M.J., Kucharczyk W., Sherar M.D. and Henkelman R.M. (1997)
Medical Physics 24, 269-277

 
1996
 

1. Blood flow cooling and ultrasonic lesion formation
Kolios M.C., Sherar M.D. and Hunt J.W. (1996)
Medical Physics 23(7), 1287-98

 
1995
 

1. Large vessel cooling in heated tissues: a numerical study
Kolios M.C., Sherar M.D. and Hunt J.W. (1995)
Physics in Medicine and Biology 40, 1-18

 
1992
 

1. Influence of transition rates and scan rate on kinetic simulations of differential scanning calorimetry profiles of reversible and irreversible protein denaturation
Lepock J.R., Ritchie K.P., Kolios M.C., Rodahl A.M., Heinz K.A., and Kruuv J. (1992)
Biochemistry 31(50), 12706-12

BOOK CHAPTERS

        1. Probing Different Biological Length Scales Using Photoacoustics: From 1 To 1000 MHz
          Eno Hysi, Eric M. Strohm , Michael C. Kolios (2014)
          Handbook of Photonics for Biomedical Engineering
          Edited by: Aaron H.-P. Ho, Donghyun Kim, Michael G. Somekh
          ISBN 978-94-007-6174-2/ DOI 10.1007/978-94-007-6174-2_29-3
        2. Quantitative Ultrasound and Cell Death
          Omar Falou, Ali Sadeghi-Naini, Azza Al-Mahrouki, Michael C. Kolios and Gregory J. Czarnota (2013)
          Quantitative Ultrasound of Soft Tissue
          Edited by: Jonthan Mamou / Michael L. Oelze © Springer
          ISBN 978-94-007-6951-9 / ISBN 978-94-007-6952-6 / DOI 10.1007/978-94-007-6952-6
        3. Acoustic microscopy of cells
          E.M. Strohm, G. Czarnota, M.C. Kolios (2013)
          Quantitative Ultrasound of Soft Tissue
          Edited by: Jonthan Mamou / Michael L. Oelze © Springer
          ISBN 978-94-007-6951-9 / ISBN 978-94-007-6952-6 / DOI 10.1007/978-94-007-6952-6
        4. Ultrasound imaging of apoptosis: spectroscopic detection of DNA-damage effects at high and low frequencies.
          Vlad RM, Kolios MC, Czarnota GJ. (2011)
          Methods in Molecular Biology Volume 682, Part 3, 165-187
          Edited by: V. V. Didenko © Humana Press Inc., Totowa, NJ
          DOI: 10.1007/978-1-60327-409-8_13
        5. Ultrasound Imaging of Apoptosis: DNA Damage Visualized
          Czarnota, G.J. Kolios, M.C. Hunt, J.W. and Sherar, M.D (2002)
          in Methods in Molecular Biology, vol. 203: In Situ Detection of DNA Damage: Methods and Protocols Edited by: V. V. Didenko © Humana Press Inc., Totowa, NJ

      DOI: 10.1385/1-59259-179-5:257

 

CONFERENCE PAPERS (PEER REVIEWED)

      1. Temperature Dependent Properties and Ultrasound Thermal Therapy
        Kolios M.C., Sherar M.D. and Hunt J.W. (1999)
        In E.P. Scott (Ed.) Advances in Heat and Mass Transfer in Biotechnology
        HTD-Vol.363 / BED- Vol.44, 113-118. American Society of Mechanical Engineers.
      2. The Effect of Heat Induced Changes in Microwave Tissue Properties on Thermal Therapy for Prostate Cancer
        Sherar M.D., Chin, L. Kolios M.C. and Gladman, A.S. (1999)
        In E.P. Scott (Ed.) Advances in Heat and Mass Transfer in Biotechnology HTD-Vol.363 / BED-Vol.34, 109-112. American Society of Mechanical Engineers.
      3. Monitoring tissue response to photodynamic therapy: The potential of minimally invasive electrical impedance spectroscopy and high frequency ultrasound
        Wilson B.C., Molckovsky A., Czarnota G.J., Sherar M.D., Kolios M.C. Lilge, L. Dattani R.S., Osterman K.S., Paulsen K.D., Hoopes P.J. (1999)
        In S.L. Jacques (Ed.) Proceedings of the 1999 SPIE, Vol. 3592 , 73-82.
      4. Thermal model predictions of ultrasonic lesion formation  ( Postscript file, better font)
        Kolios M.C., Sherar M.D. and Hunt J.W. (1995)
        In L.J. Hayes (Ed.), Advances in Bioheat and Mass Transfer in Biotechnology , HTD-Vol.322 / BED-Vol.32, 139-144. American Society of Mechanical Engineers.
      5. Modeling temperature gradients near large vessels in perfused tissues
        (Postscript file, better font)
        Kolios, M.C. Sherar, M.D Worthington, A. E. and Hunt, J.W. (1994)
        In M. Ebadian and P. Oosthuizen (Eds.), Fundamentals of Biomedical Heat Transfer, HTD-Vol. 295, 23-30. American Society of Mechanical Engineers.

CONFERENCE PAPERS (NON PEER-REVIEWED)

         2017

    1. Application of image flow cytometry for the characterization of red blood cell morphology
      Ruben N. Pinto; Joseph A. Sebastian; Michael Parsons; Tim C. Chang; Jason P. Acker; Michael C. Kolios
      Proc. SPIE 10076, High-Speed Biomedical Imaging and Spectroscopy: Toward Big Data Instrumentation and Management II, 100761F (22 February 2017); doi: 10.1117/12.2253583
    2. Photoacoustic measurements of red blood cell oxygen saturation in blood bags in situ
      Ruben N. Pinto ; Karan Bagga ; Alexandre Douplik ; Jason P. Acker ; Michael C. Kolios
      Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 1006440 (March 3, 2017); doi:10.1117/12.2253530
    3. Multispectral photoacoustic bioimaging using low power continuous wave lasers
      K. Sathiyamoorthy Eric M. Strohm and Michael C. Kolios
      Proc. of SPIE Vol. 10064  100644M-1 doi: 10.1117/12.2252598
    4. Rapid computation of photoacoustic fields from normal and pathological red blood cells using a Green’s function method
      Ratan K. Saha, Muhannad N. Fadhel, Aamna Lawrence, Subhajit Karmakar, Arunabha Adhikari, and Michael C. Kolios
      Proc.of SPIE Vol. 10064, 100644U  doi: 10.1117/12.2253555
    5. Spatial interference encoding patterns based super resolved photoacoustic microscopy
      Amihai Meiri, Eric M. Strohm, Michael C. Kolios and Zeev Zalevsky
      Proc. of SPIE Vol. 10064, 1006453 doi: 10.1117/12.2251675
    6. Quantitative photoacoustic assessment of red blood cell aggregation under pulsatile blood flow: experimental and theoretical approaches
      Tae-Hoon Bok, Eno Hysi, Michael C. Kolios
      Proc.of SPIE Vol. 10064, 100645F doi: 10.1117/12.22502212016
    7. Single red blood cell oxygenation saturation imaging with multispectral photoacoustic microscopy
      Moore, M.J.Schygulla, P.M.Strohm, E.M.Kolios, M.C.
      2016 IEEE International Ultrasonics Symposium; DOI: 10.1109/ULTSYM.2016.7728869
    8. High frequency ultrasound imaging and spectral analysis of sea urchin oocytes
      Strohm, E.M.Wirtzfeld, L.A.,  Czarnota, G.J.,  Kolios, M.C.
      2016 IEEE International Ultrasonics Symposium; DOI: 10.1109/ULTSYM.2016.7728710
    9. High frequency photoacoustic spectral analysis of erythrocyte programmed cell death (eryptosis)
      Fadhel, M.N.Strohm, E.M.Kolios, M.C.
      2016 IEEE International Ultrasonics Symposium; DOI: 10.1109/ULTSYM.2016.7728865
    10. Ultrasound and photoacoustic analysis of cell pellets at 200 MHz
      Wirtzfeld, L.A.Strohm, E.M.Kolios, M.C.
      2016 IEEE International Ultrasonics Symposium; DOI: 10.1109/ULTSYM.2016.7728644
    11. Steering the receiving field of view (FOV) without applying delays insynthetic transmit aperture imaging (STA)
      Li, Y. Kolios, M.C.,  Xu, Y.
      2016 IEEE International Ultrasonics Symposium; DOI: 10.1109/ULTSYM.2016.7728492
    12. Plane-wave imaging using synthetic aperture imaging reconstruction technique with regularized singular-value decomposition (RSVD)
      Li, Y.,  Yang, D-M, Kolios, M.C.,  Xu, Y.
      2016 IEEE International Ultrasonics Symposium; DOI: 10.1109/ULTSYM.2016.7728888
    13. Differentiation between cellularized and decellularized mouse kidneys using mean scatterer spacing: A preliminary study
      Remie Nasr; Omar Falou; Eno Hysi; Lauren Wirtzfeld; Elizabeth S. L. Berndl; Michael C. Kolios
      3rd Middle East Conference on Biomedical Engineering (MECBME); DOI: 10.1109/MECBME.2016.7745422
    14. Photoacoustic investigation of gold nanoshells for bioimaging applications
      K. Sathiyamoorthy ; Eric M. Strohm and Michael C. Kolios
      Proc. SPIE 9724, Plasmonics in Biology and Medicine XIII, 97240L (March 7, 2016); doi:10.1117/12.2213766
    15. Large-pitch steerable synthetic transmit aperture imaging (LPSSTA)
      Ying Li ; Michael C. Kolios and Yuan Xu
      Proc. SPIE 9790, Medical Imaging 2016: Ultrasonic Imaging and Tomography, 97901Y (April 1, 2016); doi:10.1117/12.2216908
    16. One-layer microfluidic device for hydrodynamic 3D self-flow-focusing operating in low flow speed
      Yasaman Daghighi ; Vaskar Gnyawali ; Eric M. Strohm ; Scott S. H. Tsai and Michael C. Kolios
      Proc. SPIE 9705, Microfluidics, BioMEMS, and Medical Microsystems XIV, 970505 (March 18, 2016); doi:10.1117/12.2212892
    17. Measuring intracellular motion in cancer cell using optical coherence tomography
      Azhar Zam and Michael C. Kolios
      Proc. SPIE 9707, Dynamics and Fluctuations in Biomedical Photonics XIII, 97070V (March 17, 2016); doi:10.1117/12.2209652
    18. Classification of biological cells using a sound wave based flow cytometer
      Eric M. Strohm ; Vaskar Gnyawali ; Mia Van De Vondervoort ; Yasaman Daghighi ; Scott S. H. Tsai and Michael C. Kolios
      Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97081A (March 15, 2016); doi:10.1117/12.2211740
    19. Acoustic and photoacoustic microscopy imaging of single leukocytes
      Eric M. Strohm ; Michael J. Moore and Michael C. Kolios
      Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97082G (March 15, 2016); doi:10.1117/12.2211759
    20. Photoacoustic spectral analysis to sense programmed erythrocyte cell death (eryptosis) for monitoring cancer response to treatment
      Muhannad N. Fadhel ; Fayruz Kibria and Michael C. Kolios
      Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97080O (March 15, 2016); doi:10.1117/12.2211760
    21. Simultaneous photoacoustic and optical attenuation imaging of single cells using photoacoustic microscopy
      Michael J. Moore ; Eric M. Strohm and Michael C. Kolios
      Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 970850 (March 15, 2016); doi:10.1117/12.2212961
    22. Biodegradable polymer based theranostic agents for photoacoustic imaging and cancer therapy
      Yan J. Wang ; Eric M. Strohm and Michael C. Kolios
      Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 970826 (March 15, 2016); doi:10.1117/12.2212999
    23. Effect of optical wavelength on photoacoustic investigations of pulsatile blood flow
      Tae-Hoon Bok ; Eno Hysi and Michael C. Kolios
      Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97081M (March 15, 2016); doi:10.1117/12.2212108
    24. Photoacoustic simulation of microvessel bleeding: spectral analysis and its implication for monitoring vascular-targeted treatments
      Muhannad N. Fadhel ; Eno Hysi ; Jason Zalev and Michael C. Kolios
      Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97081B (March 15, 2016); doi:10.1117/12.2211774
      2015
    25. Evaluation of the Morphological Parameters of Cancer Cells Using High-Frequency Ultrasound and Photoacoustics
      Michael J. Moore, Eric M. Strohm, and Michael C. Kolios
      In 2015 IEEE International Ultrasonics Symposium Proceedings – 10.1109/ULTSYM.2015.0246
    26. Low Power Continuous Wave Photoacoustic Microscope for Bioimaging Applications
      K. Sathiyamoorthy and Michael C. Kolios
      In 2015 IEEE International Ultrasonics Symposium Proceedings – 10.1109/ULTSYM.2015.0398
    27. Nonlinear Model of Acoustical Attenuation and Speed of Sound in a Bubbly Medium.
      Amin Jafari Sojahrood, Hossein Haghi, Raffi Karshafian, Michael C. Kolios
      In 2015 IEEE International Ultrasonics Symposium Proceedings – 10.1109/ULTSYM.2015.0086
    28. Reducing the Number of Receiving Channels Using Transmit-Receive Symmetry in Synthetic Transmit Aperture Imaging
      Ying Li, Ping Gong, Michael C. Kolios, Yuan Xu
      In 2015 IEEE International Ultrasonics Symposium Proceedings -10.1109/ULTSYM.2015.0306
    29. Simulation Studies of Filtered Spatial Compounding (FSC) and Filtered Frequency Compounding (FFC) in Synthetic Transmit Aperture (STA) Imaging
      Ping Gong, Michael C. Kolios, Yuan Xu
      In 2015 IEEE International Ultrasonics Symposium Proceedings -10.1109/ULTSYM.2015.0197
    30. Ultrasonic Characterization of Extra-Cellular Matrix in Decellularized Murine Kidney and Liver
      L. A. Wirtzfeld, E. S. L. Berndl, M. C. Kolios
      In 2015 IEEE International Ultrasonics Symposium Proceedings – 10.1109/ULTSYM.2015.0170
    31. Probing the in vivo changes in oxygen saturation with photoacoustic imaging as a non-invasive means of assessing treatment progression
      Eno Hysi, Jonathan P. May, Lauren Writzfeld, Elijus Undyzs, Shyh-Dar Li, Michael C. Kolios
      Proc. of SPIE Vol. 9323, 93231Z (doi: 10.1117/12.2080372)
    32. High-frequency photoacoustic imaging of erythrocyte aggregation and oxygen saturation: probing hemodynamic relations under pulsatile blood flow
      Tae-Hoon Bok, Eno Hysi, Michael C. Kolios
      Proc. of SPIE Vol. 9323, 93231Q (doi: 10.1117/12.2076650)
    33. Gold-nanoshells as surface plasmon resonance (SPR)
      K. Sathiyamoorthy and Michael C. Kolios
      Proc. of SPIE Vol. 9332, 93320G (doi: 10.1117/12.2080303)
    34. Numerical investigation of plasmonic properties of gold nanoshells
      K. Sathiyamoorthy and Michael C. Kolios
      Proc. of SPIE Vol. 9340, 93400V (doi: 10.1117/12.2080428)
    35. Realistic photoacoustic image simulations of collections of solid spheres using linear array transducer
      Subhajit Karmakar, Eno Hysi, Michael C. Kolios and Ratan K. Saha
      Proc. of SPIE Vol. 9323, 932339 (doi: 10.1117/12.2080794)
    36. Multifunctional perfluorocarbon nanoemulsions for cancer therapy and imaging
      Donald A. Fernandes, Dennis D. Fernandes, Yan J. Wang, Yuchong Li, Claudiu C. Gradinaru, Dérick Rousseau, Michael C. Kolios
      Proc. of SPIE Vol. 9338, 93380R (doi: 10.1117/12.2079914)
    37. Mean scatterer spacing estimation from pellets using cepstral analysis: A preliminary study
      Remie Nasr, Omar Falou, Lauren Wirtzfeld, Elizabeth Berndl and Michael Kolios
      2015 International Conference on Advances in Biomedical Engineering (ICABME) Article number 7323313, Pages 305-308 (doi:10.1109/ICABME.2015.7323313)
    38. Photoacoustic speckle and spectral analysis of vasculature trees
      Muhannad Fadhel, and Michael C. Kolios
      IFMBE Proceedings World Congress on Medical Physics and Biomedical Engineering Volume 51, 2015, Pages 1084-1087 (DOI: 10.1007/978-3-319-19387-8_264)2014

       

    39. Laser-activated PLGA theranostic agents for cancer therapy in vivo
      Yang Sun, Yan Wang, Chengcheng Nui, Eric Strohm, Yuanyi Zheng, Haitao Ran, Dong Wang, Rongzhong Huang, Yuping Gong, Di Zhou, Zhigang Wang, Michael Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 919-922
    40. Development of a microfluidic device with integrated high frequency ultrasound probe for particle characterization
      Eric Strohm, Byeong-Ui Moon, Dae Kun Hwang, Scott Tsai and Michael Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 1960-1963
    41. Ultra-High Frequency Acoustic Impedance Imaging of Cancer Cells
      Muhannad Fadhel, Elizabeth Berndl, Eric Strohm and Michael Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 1912-1915
    42. Assessing storage-induced red blood cell lesions using photoacoustic measurements of oxygen saturation and the frequency content of photoacoustic signals
      Eno Hysi, Eric M. Strohm, Elizabeth S. L. Berndl, Jason P. Acker, Michael C. Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 1662-1665
    43. In vitro study of PLGA/PFH  particles loaded with gold nanoparticles as theranostic agents for photoacoustic imaging and cancer therapy
      Yan Wang, Eric Strohm, Yang Sun, Yuanyi Zheng, Zhigang Wang and Michael Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 1658-1661
    44. Effective scatterer size estimates in HT-29 spheroids at 55 MHz and 80 MHz
      Lauren A. Wirtzfeld, Elizabeth S. L. Berndl, Gregory J. Czarnota and Michael C. Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 632-635
    45. Quantitative ultrasound analyses of cell starvation in HT-29 pellets
      Lauren A. Wirtzfeld, Elizabeth S. L. Berndl, Gregory J. Czarnota and Michael C. Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 620-623
    46. Longitudinal monitoring of  oxygen saturation with photoacoustic imaging:  An early, functional indicator of  the in  vivo efficacy of thermosensitive liposome treatments
      Eno Hysi, Jonathan P. May, Lauren Wirtzfeld, Elijus Undzys, Shyh-Dar Li and Michael C. Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 357-360
    47. Temperature dependence of the Harmonics Generated by Nonlinear Ultrasound Beam Propagation in Water: A Simulation Study
      Borna Maraghechi, Mojtaba H. Hasani,  Michael C. Kolios and Jahan Tavakkoli
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 1456-1459
    48. Simultaneous  measurement  of  erythrocyte aggregation and oxygen saturation under in vitro pulsatile blood flow by  high-frequency photoacoustics
      Tae-Hoon Bok, Eno Hysi and Michael Kolios
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 1292-1295
    49. Delay-encoded Transmission in Synthetic Aperture Imaging (DE-SAI)
      Ping Gong, Arash Moghimi, Michael Kolios and Yuan Xu
      In 2014 IEEE International Ultrasonics Symposium Proceedings pp. 1005-1008
    50. A Low-cost High-SNR Ultrasound Imager: Modified Hadamard Synthetic Aperture Imaging (MH-SAI) System with a Sparse Receiving Array
      Ping Gong, Michael Kolios, Yuan XuIn 2014 IEEE International Ultrasonics Symposium Proceedings pp. 1658-1661
    51. Quantifying Temperature Changes in Tissue-Mimicking Fluid Phantoms using Optical Coherence Tomography and Envelope
      Statistics

      Subaagari Seevaratnam, Amitpal Bains, Mashal Farid, Golnaz Farhat, Michael Kolios, Beau A. Standish
      Proc. of SPIE Vol. 8938, 89380R
    52. Detecting apoptosis in vivo and ex vivo using spectroscopic OCT and dynamic light scattering
      Golnaz Farhat, Anoja Giles, Adrian Mariampillai, Victor X. D. Yang,  Gregory J. Czarnota and Michael C. Kolios
      Proc. of SPIE Vol. 8952, 89520K
    53. Circulating tumor cell detection using photoacoustic spectral methods
      Eric M. Strohm, Elizabeth S. L. Berndl, Michael C. Kolios
      Proc. of SPIE Vol. 8943, 89430D
    54. Photoacoustic tissue characterization using envelope statistics and ultrasonic spectral parameters
      Eno Hysi, Dustin Dopsa, Michael C. Kolios
      Proc. of SPIE Vol. 8943, 89432E
    55. PLGA/PFC Particles Loaded with Gold Nanoparticles as Dual Contrast Agents for Photoacoustic and Ultrasound Imaging
      Yan J. Wang, Eric M. Strohm, Yang Sun, Chengcheng Niu, Yuanyi Zheng, Zhigang Wang, Michael C. Kolios
      Proc. of SPIE Vol. 8943, 89433M
    56. Identification of red blood cell rouleaux formation using photoacoustic ultrasound spectroscopy
      Fayruz Kibria, Eno Hysi, Eric M. Strohm and Michael C. Kolios
      Proc. of SPIE Vol. 8943, 894367
    57. Optical Coherence Tomography detection of shear wave propagation in MCF7 cell modules
      Marjan Razani, Adrian Mariampillai, Elizabeth  S.L. Berndl, Tim-Rasmus Kiehl, Victor X.D. Yang, Michael C. Kolios
      Proc. of SPIE Vol. 8946, 8946102013
    58. Vaporization, photoacoustic and acoustic characterization of PLGA/PFH particles loaded with optically absorbing materials
      Sun, Yang; Wang, Yan; Niu, Chengcheng; Strohm, Eric; Zheng, Yuanyi; Ran, Haitao; Wang, Zhigang; Kolios, Michael
      In 2013 IEEE International Ultrasonics Symposium Proceedings pp. 132-135
    59. Nonlinear Dynamics of Polymer Shell Ultrasound Contrast Agents at 8-32 MHz Ultrasonic Excitations
      Sojahrood, Amin Jafari; Karshafian, Raffi; Stride, Eleanor; Kolios, Michael
      In 2013 IEEE International Ultrasonics Symposium Proceedings pp. 314-317
    60. Photoacoustic assessment of oxygen saturation: effect of red blood cell aggregation
      Eno Hysi, Ratan K. Saha and Michael C. Kolios
      Proc. of SPIE Vol. 8581, 85813T
    61. Photoacoustic radio-frequency spectroscopy (PA-RFS): A technique for monitoring absorber size and concentration
      Eno Hysi, Dustin Dopsa, and Michael C. Kolios
      Proc. of SPIE Vol. 8581, 85813W
    62. Classifying Normal and Abnormal Vascular Tissues using Photoacoustic Signals
      Behnaz Pourebrahimi, Azza Al-Mahrouki, Jason Zalev, Joris T. Nofiele, Gregory J. Czarnota and Michael C. Kolios
      Proc. of SPIE Vol. 8581, 858141
    63. Improving the Quality of Photoacoustic Images using the Short-Lag Spatial Coherence Imaging Technique
      Behanz Pourebrahimi, Sangpil Yoon, Dustin Dopsa, Michael C. Kolios
      Proc. of SPIE Vol. 8581, 85813Y
    64. Optical Coherence Tomography detection of shear wave propagation in layered tissue equivalent phantoms
      Marjan Razani, Adrian Mariampillai, Peter Siegler ,Victor X.D. Yang, Michael C. Kolios
      Proc. of SPIE Vol. 8565, 85654Q
    65. A photoacoustic technique to measure the properties of single cells
      Eric M. Strohm, Elizabeth S. L. Berndl, Michael C. Kolios 
      Proc. of SPIE Vol. 8581, 85814D ·2012
    66. Detection and characterization of higher order nonlinearities in the oscillations of Definity at higher frequencies and very low acoustic pressures
      Amin Jafari Sojahrood, Raffi Karshafian, Michael C. Kolios (2012)
      In 2012 IEEE International Ultrasonics Symposium Proceedings pp. 1193-1196
    67. Numerical and experimental classification of the oscillations of single isolated microbubbles: occurrence of higher order subharmonics
      Amin Jafari Sojahrood, Raffi Karshafian, Michael C. Kolios (2012)
      In 2012 IEEE International Ultrasonics Symposium Proceedings pp. 402-405
    68. Simultaneous Photoacoustic Detection of Red Blood Cell Aggregation and Oxygenation
      Eno Hysi, Ratan K. Saha and Michael C. Kolios (2012)
      In 2012 IEEE International Ultrasonics Symposium Proceedings pp. 1398-1401
    69. Photoacoustic measurements of single red blood cells
      Eric M. Strohm, Eno Hysi, Michael C. Kolios (2012)
      In 2012 IEEE International Ultrasonics Symposium Proceedings pp. 1406-1409
    70. Measuring intracellular motion using dynamic light scattering with optical coherence tomography in a mouse tumor model
      Golnaz Farhat, Adrian Mariampillai, Kenneth K. C. Lee, Victor X. D. Yang,  Gregory J. Czarnota and Michael C. Kolios (2012)
      Proc. of SPIE Vol. 8230, 823002-1:7
    71. Biomechanical properties of soft tissue measurement using Optical  Coherence Elastography
      Marjan Razani, Adrian Mariampillai, Cuiru Sun, Victor X.D. Yang, Michael C. Kolios (2012)
      Proc. of SPIE  Vol. 8207, 820758-1:8
    72. On the potential of using photoacoustic spectroscopy for monitoring red blood cell aggregation
      Eno Hysi, Ratan K. Saha, and Michael C. Kolios (2012)
      Proc. of SPIE Vol. 8222  82220Q-10
    73. Frequency Analysis of Optoacoustic Signals in Laser Heated Tissues
      Annie Ladéroute, Michelle P. Patterson, Michael C. Kolios, William M. Whelan (2012)
      Proc. of SPIE Vol. 8223 822341-1
    74. Photoacoustic spectral characterization of perfluorocarbon droplets
      Eric Strohm, Ivan Gorelikov, Naomi Matsuura, Michael Kolios (2012)
      Proc. of SPIE Vol. 8223 82232F-1
    75. Detection and characterization of red blood cell (RBC) aggregation with photoacoustics
      Eno Hysi, Ratan K. Saha, Min Rui and Michael C. Kolios (2012)
      Proc. of SPIE Vol. 8223 82233E-1
    76. Optimization of the shear stress induced by ultrasonically-stimulated oscillating MBs: A theoretical investigation
      Amin Jafari Sojahrood, Raffi Karshafian, and Michael C. Kolios
      11th International Symposium on Therapeutic Ultrasound / AIP Conf. Proc. 1481, 351 (2012); doi: 10.1063/1.47573602011

       

    77. Optoacoustic signal amplitude and frequency spectrum analysis laser heated bovine liver ex vivo
      Michelle P. Patterson, Christopher B. Riley, Michael C. Kolios and William M. Whelan (2012)
      In 2011 IEEE International Ultrasonics Symposium Proceedings  pp. 300-303
    78. Characterization of Red Blood Cell Aggregation with Photoacoustics: A Theoretical and Experimental Study
      Eno Hysi, Ratan K. Saha and Michael C. Kolios
      In 2011 IEEE International Ultrasonics Symposium Proceedings  pp. 1187-1190
    79. Sound velocity and attenuation measurements of  perfluorocarbon liquids using photoacoustic methods
      Eric M. Strohm and Michael C. Kolios
      In 2011 IEEE International Ultrasonics Symposium Proceedings  pp.2368
    80. A Monte Carlo study on the effects of erythrocyte oxygenation on photoacoustic signals
      Ratan K. Saha and Michael C. Kolios
      In 2011 IEEE International Ultrasonics Symposium Proceedings pp. 2372-2375
    81. Ultrasound drug targeting to tumors with thermosensitive liposomes
      Mark J. Ernsting, Arthur Worthington, Jonathan P. May, Tatsuaki Tagami, Michael C. Kolios, Shyh-Dar Li
      In 2011 IEEE International Ultrasonics Symposium Proceedings pp. 1-4
    82. Detecting abnormal vasculature from photoacoustic signals using wavelet-packet features
      Jason Zalev and Michael C. Kolios (2011)
      Proc. of SPIE Vol. 7899 78992M-1:15
    83. Cell death monitoring using quantitative optical coherence tomography methods
      Golnaz Farhat, Victor X. D. Yang, Michael C. Kolios and Gregory J. Czarnota (2011)
      Proc. of SPIE Vol. 7907 790713-1:9
    84. Optical coherence tomography speckle decorrelation for detecting cell death
      Golnaz Farhat, Adrian Mariampillai, Victor X. D. Yang, Gregory J. Czarnota and Michael C. Kolios (2011)
      Proc. of SPIE Vol. 7907 790710-1:10
    85. Optical Droplet Vaporization of Micron-sized Perfluorocarbon Droplets and their Photoacoustic Detection
      Eric Strohm, Min Rui, Ivan Gorelikov, Naomi Matsuura, Michael Kolios (2011)
      Proc. of SPIE Vol. 7899 78993H-1:7
    86. Dynamics of laser induced thermoelastic expansion of native and coagulated ex-vivo soft tissue samples and their optical and thermomechanical properties
      Behrouz Soroushian, William M. Whelan, Michael C. Kolios (2011)
      Proc. of SPIE Vol. 7899 78990Z-1:5
      2010
    87. A comparison of cellular ultrasonic properties during apoptosis and mitosis using acoustic microscopy
      Eric M. Strohm, Maurice Pasternak, Michelle Mercado, Min Rui, Gregory J. Czarnota and Michael C. Kolios (2010)
      In 2010 IEEE International Ultrasonics Symposium Proceedings  pp. 608-611
    88. Optical Droplet Vaporization (ODV): photoacoustic characterization of perfluorocarbon droplets
      Eric M. Strohm, Min Rui, Ivan Gorelikov, Naomi Matsuura and Michael C. Kolios (2010)
      In 2010 IEEE International Ultrasonics Symposium Proceedings  pp. 495-498
    89. A Simulation Study on Ultrasound Backscattering by Cell Aggregates with Poly-disperse Cells
      Ratan K Saha and Michael C. Kolios (2010)
      In 2010 IEEE International Ultrasonics Symposium Proceedings  pp. 2307-2310
    90. Photoacoustic Microscopy and Spectroscopy of Individual Red Blood Cells
      Min Rui, Wolfgang Bost, Eike C. Weiss, Robert Lemor and Michael C. Kolios (2010)
      OSA – Optics & Photonics Congress:  BIOMED/DH 2010 – BSuD93
    91. Quantitative Optical Coherence Tomography Imaging of Cell Death
      Golnaz Farhat, Victor X.D. Yang, Michael C. Kolios, and Gregory J. Czarnota (2010)
      OSA – Optics & Photonics Congress: BIOMED/DH 2010 – JMA47
    92. Speckle Decorrelation as a Method for Assessing Cell Death
      Golnaz Farhat, Adrian Mariampillai, Victor X.D. Yang, Gregory J. Czarnota and Michael C. Kolios (2010)
      OSA – Optics & Photonics Congress: BIOMED/DH 2010 – BSuD12
    93. Gigahertz optoacoustic imaging for cellular imaging
      Min Rui, Sankar Narashimhan, Wolfgang Bost, Frank Stracke, Eike Weiss, Robert Lemor and Michael C. Kolios (2010)
      Photons Plus Ultrasound: Imaging and Sensing 2010, edited by Alexander A. Oraevsky, Lihong V. Wang,
      Proc. of SPIE Vol. 7564, 756411
    94. Optoacoustic imaging of an animal model of prostate cancer
      Michelle P. Patterson Michel G. Arsenault, Chris Riley, Michael Kolios and William M. Whelan (2010)
      Photons Plus Ultrasound: Imaging and Sensing 2010, edited by Alexander A. Oraevsky, Lihong V. Wang,
      Proc. of SPIE Vol. 7564, 75641B
    95. Dynamics of thermoelastic expansion for native and coagulated ex-vivo bovine liver tissues
      Behrouz Soroushian, William M. Whelan, Michael C. Kolios (2010)
      Photons Plus Ultrasound: Imaging and Sensing 2010, edited by Alexander A. Oraevsky, Lihong V. Wang,
      Proc. of SPIE Vol. 7564, 75641N
    96. A Theoretical Model for RF Ablation of Kidney Tissue and Its Experimental Validation
      Mihaela Pop, Sean R.H. Davidson, Mark Gertner, Michael A.S. Jewett, Michael D. Sherar and Michael C Kolios (2010)
      Lecture Notes in Computer Science, Volume 5958, p 119-129
      2009
    97. Quantifying the Ultrasonic Properties of Cells During Apoptosis using Time Resolved Acoustic Microscopy
      Eric M. Strohm, Michael C. Kolios (2009)
      In 2009 IEEE International Ultrasonics Symposium Proceedings  pp. 49-52
    98. A Novel Technique for Measuring Ultrasound Backscatter from Single Micron-Sized Objects
      Omar Falou, Min Rui, Ahmed El-Kaffas, J. Carl Kumaradas and Michael C. Kolios (2009)
      In 2009 IEEE International Ultrasonics Symposium Proceedings  pp. 49-52
    99. Signal analysis for the estimation of mechanical parameters of viable cells using GHz-acoustic microscopy
      Sebastian Brand, Nick Grube, Kay Raum, Eric M. Strohm and  Michael C. Kolios (2009)
      In 2009 IEEE International Ultrasonics Symposium Proceedings  pp. 2248-2251
    100. Biomedical Ultrasound Imaging: from 1 to 1000 MHz.
      [plenary presentation] Michael C. Kolios (2009)
      Canadian Acoustics / Acoustique Canadienne Vol. 37(3), 35- 42
    101. Measuring scattering in apoptotic cnacer cells using ultra high freqeuncy acoustic microscopy
      Eric Strohm, Michael Kolios (2009)
      Canadian Acoustics / Acoustique Canadienne Vol. 37(3), 168-169
    102. A comparison of imaging modalities to monitor thermal and mechanical ultrasound tissue therapies
      Arthur Worthington, Sankar Narasimhan, Jahan Tavakkoli, and Michael C. Kolios (2009)
      Canadian Acoustics / Acoustique Canadienne
      Vol. 37(3), 170-171
    103. High Frequency Optoacoustic Microscopy
      Wolfgang Bost, Frank Stracke, Eike C. Weiß, Sankar Narasimhan, Michael C. Kolios and Robert Lemor (2009)
      In 31st Annual International Conference of the IEEE EMBS, 5883-5886
    104. Measuring the Mechanical Properties of Cells using Acoustic Microscopy
      Eric M. Strohm, Michael C. Kolios (2009)
      In 31st Annual International Conference of the IEEE EMBS, 6042-6045
    105. Assessment of opto-mechanical behavior of biological samples by interferometry
      Behrouz Soroushian, William M. Whelan, Michael C. Kolios (2009)
      In Photons Plus Ultrasound: Imaging and Sensing 2009, edited by Alexander A. Oraevsky, Lihong V. Wang,
      Proc. of SPIE Vol. 7177, 71771X
    106. Optoacoustic detection of thermal lesions
      Michel G. Arsenault, Michael C. Kolios and William M. Whelan (2009)
      In Photons Plus Ultrasound: Imaging and Sensing 2009, edited by Alexander A. Oraevsky, Lihong V. Wang,
      Proc. of SPIE Vol. 7177, 71771V
      2008
    107. Photoacoustic detection of protein coagulation in albumen-based phantoms
      Robin F. Castelino, William M. Whelan, and Michael C. Kolios (2008)
      In Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, edited by Alexander A. Oraevsky, Lihong V. Wang,
      Proc. SPIE 6856, 685626
    108. New Insights into High Frequency Ultrasonic Tissue Scattering
      M.C. Kolios and G.J. Czarnota (2008)
      In 3rd International Symposium on Medical, Bio- and Nano-Electronics, Sendai, Japan, OC-4
    109. High frequency ultrasound scattering from mixtures of two different cells lines: tissue characterization insights
      M.C. Kolios and G.J. Czarnota (2008)
      In 11th International Symposium on Advanced Biomedical Ultrasound, Sendai, Japan, pp. 23-25
      2007
    110. Finite-element Modeling of Elastic Surface Modes and Scattering from Spherical Objects
      O. Falou, J. C. Kumaradas and M. C. Kolios (2007)
      Proceedings of the COMSOL Users Conference 2006, Boston
    111. Extended system transfer compensation for parametric imaging in ultrasonic response assessment of anti-cancer therapies
      S. Brand, G. J. Czarnota and M.C.Kolios (2007)
      In Proceedings of the 2007 IEEE International Ultrasonics Symposium, pp.2481-2484
    112. Transmission Ultrasound to guide Minimally Invasive Thermal Therapy
      E. Soleimankhani and M.C.Kolios (2007)
      In Proceedings of the 2007 IEEE International Ultrasonics Symposium, pp.2481-2484
    113. Two-Dimensional Velocity Estimation for Doppler Optical Coherence Tomography
      Darren Morofke, Michael C. Kolios, Victor X.D. Yang,
      Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI
      edited by James G. Fujimoto, Joseph A. Izatt, Valery V. Tuchin
      Proc. of SPIE Vol. 6429, 64292F, (2007)
      2006
    114. Examination of contrast mechanisms in optoacoustic imaging of thermal lesions
      Christian Richter, Gloria Spirou, Alexander A.Oraevsky, William M. Whelan and Michael C. Kolios
      In Proceedings of SPIE — Volume 6086 Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, Alexander A. Oraevsky, Lihong V. Wang, Editors, 60861K – (2006)
      2005
    115. The Effect of Volume Fraction on the Backscatter from Nucleated Cells at High Frequencies
      R.E. Baddour and M.C. Kolios
      In Proceedings of the 2005 IEEE International Ultrasonics Symposium, Volume 2, pp.1672-74
    116. Visualization of Apoptotic Cells using Scanning Acoustic Microscopy and high frequency ultrasound
      S. Brand*, G. J. Czarnota, E. C. Weiss, R. Lemor and M.C.Kolios
      In Proceedings of the 2005 IEEE International Ultrasonics Symposium, Volume 2, Page(s):882 – 885
    117. Using High Frequency Ultrasound Envelope Statistics to Determine Scatterer Number Density in Dilute Cell Solutions
      A.S. Tunis, R. E. Baddour, G. J. Czarnota, A. Giles, A. E. Worthington, M. D. Sherar, and M. C. Kolios
      In Proceedings of the 2005 IEEE International Ultrasonics Symposium, Volume 2, pp.878-881
      2004
    118. High Frequency Ultrasound Signal Statistics From Mouse Mammary Tissue During Involution
      A.S. Tunis, D. Spurrel, D. McAlduff, A. Giles, M. Hariri, R. Khokha, M.D. Sherar, G.J. Czarnota and M.C. Kolios
      In Proceedings of the 2004 IEEE International Ultrasonics Symposium
    119. Towards understanding the nature of high frequency ultrasound backscatter from cells and tissues: an investigation of backscatter power spectra from different concentrations of cells of different sizes.
      M.C. Kolios, G.J. Czarnota, A. Worthington, A. Giles, A.S. Tunis and M.D. Sherar
      In Proceedings of the 2004 IEEE International Ultrasonics Symposium
    120. High frequency ultrasound in monitoring suitability for transplantation
      R.M. Vlad, G.J. Czarnota, A. Giles, M.D. Sherar, J.W. Hunt and M.C. Kolios
      In Proceedings of the 2004 IEEE International Ultrasonics Symposium 
    121. Attenuation Mapping for Monitoring Thermal Therapy Using Ultrasound Transmission Imaging
      N. Parmar and M.C.Kolios
      In Proceedings of the 26th Annual International Conference of the IEEE EMBS (2004), pp. 1329-1332
      2003
    122. Ultrasound Backscatter Signal Characterization and Classification Using Autoregressive Modeling and Machine Learning Algorithms
      N.R. Farnoud, S. Krishnasn and M.C. Kolios
      In Proceedings of the 25th Annual International Conference of the IEEE EMBS (2003), pp. 2861-2864
    123. An Investigation of Backscatter Power Spectra from Cells, Cell Pellets and Microspheres
      M.C. Kolios, L. Taggart, R..E. Baddour, F.S. Foster, J.W. Hunt, G.J. Czarnota and M.D. Sherar
      In Proceedings of the 2003 IEEE International Ultrasonics Symposium
      2002
    124. High Frequency Ultrasound Imaging of Changes in Cell Strucutre Including Apoptosis
      R.E. Baddour, M.D. Sherar, G.C. Czarnota, J.W. Hunt, L. Taggart, A. Giles, N.R. Farnoud, and M.C. Kolios
      In Proceedings of the 2002 IEEE International Ultrasonics Symposium

      2001
    125. Analysis of Ultrasound Backscatter from Ensembles of Cells and Isolated Nuclei
      M.C. Kolios, G.J. Czarnota, M. Hussain, F. S. Foster, J.W. Hunt and M.D. Sherar (2001)
      In Proceedings of the 2001 IEEE International Ultrasonics Symposium
      1997
    126. New Acoustic Beams Designed for Rapid Lesion Formation: Limitations Near the Skin During Multiple Lesion Treatments
      J.W. Hunt, A.Y. Xuan, E. Seto, A.W. Worthington, L. Chen, M.C. Kolios , and Sherar M.D. (1997)
      In Proceedings of the 1997 IEEE International Ultrasonics Symposium
    127. Spatial Correlation of Flow Induced Temperature Gradients During Tissue Heating with Vascular Geometry using CT Angiography: Implications for Thermal Therapy
      (Postscript file, better font)
      Kolios, M.C. Sherar, M.D, Worthington, A. E., Holdsworth, D.W. and Hunt, J.W. (1997)
      In Proceedings of the Canadian Organization of Medical Physicists (1997), p. 149-151
      (abstract also published in Medical Physics (24)1206, 1997)
      1996
    128. Correlation of steady state and transient temperature profiles in perfused fixed kidneys: implications for thermal models. ( Postscript file, better font)Kolios, M.C. Sherar, M.D, Worthington, A. E. and Hunt, J.W. (1996)
      In C. Franconi, G. Archangeli and R. Cavaliere (Eds.), Hyperthermic Oncology 1996, 509-511. Editorgrafica srl, Roma.

News